Niacinamide vs. Vitamin C — Which One Does Your Skin Need First?
By Siauva Editorial · June 06, 2025

Niacinamide vs. Vitamin C — Which One Comes First?
If you’ve ever stood in front of your skincare shelf wondering, “Can I even use these two together?” — you’re not alone. Niacinamide and Vitamin C are two of the most powerful glow-up ingredients in skincare, but the layering order? That’s where the glow science begins.
☀️ Meet the Actives: What They Actually Do
Niacinamide
A form of Vitamin B3 that balances oil, minimizes pores, fades dark spots, and strengthens the skin barrier — all without irritation. It’s like a therapist for your skin: calming, balancing, and always in your corner.
Vitamin C (Sodium Ascorbyl Phosphate)
This antioxidant powerhouse brightens dull skin, evens tone, and fights free radical damage from sun and pollution. Think of it as your skin’s morning espresso shot — energizing and protective.
🌤️ Can You Use Them Together?
Yes — absolutely. The old myth that Niacinamide and Vitamin C “cancel each other out” has been debunked. Modern formulations are stable enough to layer both. And when combined correctly, they actually enhance each other’s benefits.
✨ Layering 101: Which One Comes First?
In the morning: Start with Vitamin C, then layer Niacinamide.
At night: Lead with Niacinamide to calm and repair, then follow with a Vitamin C serum (or skip it if your skin is sensitive overnight).
- Step 1: Cleanser
- Step 2: Vitamin C (AM) or Niacinamide (PM)
- Step 3: Moisturizer
- Step 4: SPF (AM only!)
💡 Pro Tip:
If you’re new to actives, alternate mornings — Vitamin C on even days, Niacinamide on odd days — until your skin adjusts. Then glow on with both.
Your Skin, Your Ritual
Skincare isn’t about rules — it’s about understanding. Once you know what each ingredient does, you can build a routine that works for your skin — not against it.